The Animal Research Ethics Board (AREB) reviews and approves all proposals for research, testing, and teaching involving live animals in accordance with guidelines, policies and associated documents established by the Canadian Council for Animal Care (CCAC). The committee ensures that all animal care and handling at Grant MacEwan University is conducted in an ethical and humane manner. It approves animal use protocols and oversees the post-approval monitoring of animal use protocols.
The AREB meets minimally twice per year to fulfill the following responsibilities:
- review and approve all animal-based teaching and research projects before they begin, applying the basic Three Rs tenet of replacing, reducing and refining animal use to the greatest extent possible and working with CCAC policies and guidelines, including the CCAC Guidelines On Animal Use Protocol Review;
- review and approve institutional policies and SOPs on animal care and use;
- ensure that its terms of reference are complete and being followed; and
undertake post-approval monitoring including animal facility site visits and discuss ongoing and upcoming work, new information from the CCAC and any new elements or concerns related to the university’s animal care and use program.
The Grant MacEwan University Animal Research Ethics Board (AREB) reviews and approves all proposals for research, testing, and teaching involving live animals in accordance with guidelines, policies and associated documents established by the Canadian Council for Animal Care (CCAC). The AREB ensures that all animal care and handling at the University is conducted in an ethical and humane manner and is responsible for reviewing animal use protocols and overseeing the post-approval monitoring of animal use projects.
2.1 The AREB reports to the Director of Research Services, as delegated by the Provost and Vice President Academic.
2.2 The Provost and Vice President Academic delegates responsibility for implementation of the animal care and use program to the Director of Research Services.
2.3 The committee reports any breaches of compliance with approved animal use protocols and standard operating procedures (SOP’s) or other standards of practice that cannot be corrected by the AREB to the Provost and Vice President Academic and Director of Research Services.
3.1 The AREB has the ultimate authority over all MacEwan University animal use to:
3.1.1 Stop any objectionable procedure if it deems that an animal is experiencing unnecessary distress or pain.
3.1.2 Stop immediately any use of animals that deviates from the approved use, any non-approved procedure, or any procedure causing unforeseen pain or distress to animals.
3.1.3 Have an animal killed humanely if pain or distress caused to the animal is not part of the approved protocol and cannot be alleviated.
3.1.4 Delegate to the university veterinarian(s) the authority to treat, remove from a study or euthanize, if necessary, an animal according to the veterinarian’s professional judgment.
4.1 It is the responsibility of the AREB to:
4.1.1 Establish that no research, testing, or teaching project (including field studies) involving animals is started, and that no breeding or housing of animals occurs, without prior AREB approval of a written animal use protocol.
4.1.2 Require all animal users to complete the appropriate Application Form(s), and to ensure that the protocol form includes all the sections as identified in the CCAC policy on Terms of Reference for Animal Care Committees.
4.1.3 Ensure that prior to approval of any research or testing project, a scientific merit review is approved.
4.1.4 Ensure that prior to approval of teaching projects, a pedagogical merit review is approved.
4.1.5 Require that animal users update their protocols with any intended modifications prior to modifications commencing.
4.1.6 Ensure that animal users report any unanticipated problems or complications affecting the health and well-being of animals, as well as steps they have taken to address the problem(s), to the AREB.
4.1.7 Review and assess all new animal use protocols, requests for modifications and annual renewals in accordance with University policies and with the CCAC guidelines before they are implemented.
4.1.8 Ensure that all AREB members and animal users are aware of and have the opportunity to become familiar with the CCAC's guidelines and policy statements; relevant University policies; and federal, provincial, or municipal legislation that is applicable to the project.
4.1.9 Ensure the completion of post-approval monitoring of all animal use projects.
4.1.10 Establish procedures, commensurate with current veterinary standards, to ensure that:
--unnecessary pain or distress is avoided
--anaesthesia and analgesia are properly and effectively used
--appropriate post-operative care is provided
--all due consideration is given to animal welfare, housing, handling and care considerations including environmental enrichment
4.2 The AREB is responsible for regular (minimally every three years) review of:
4.2.1 the AREB Terms of Reference
4.2.2 the security of the animals and research facilities
4.2.3 the standard operating procedures (SOPs) and institutional animal care and use policies
4.2.4 policies and procedures for monitoring animal care and experimental procedures within the institution, including the identification of the persons responsible for monitoring animal health and welfare, and the procedures carried out by the AREB to conduct monitoring
4.3 The AREB is responsible for maintaining liaison with the CCAC Secretariat and to inform the Secretariat of any changes to the animal use program and to personnel including the senior administrator responsible for animal care and use, the AREB Chair and the veterinary and senior animal care personnel.
4.4 The AREB must submit, to the CCAC, complete and accurate animal use information using the Animal Use Data Form by March 31st each year.
4.5 The AREB shall develop and continually update a crisis management plan for the animal facilities and for the animal care and use program in conjunction with any general institutional crisis management plan(s).
4.6 The AREB shall sponsor annual seminars/workshops on the use of animals in science and the ethics of animal experimentation.
5.1 AREB members and Chair will be selected and appointed by the Provost and Vice President Academic.
5.2 AREB members will be appointed for a term of two years, except for students who may be appointed for a term of one year. Terms may be renewed to a maximum of eight consecutive years of service. Exceptions will be considered on a case-by-case basis.
5.3 AREB ex-officio members are voting members whose membership terms do not expire.
5.4 In the event that a member resigns before the conclusion of their appointed term, the Provost and Vice President Academic must appoint a replacement member as soon as possible.
5.5 The Provost and Vice President Academic may remove a member for failure to adhere to membership terms at any time.
5.6 The AREB shall be comprised of the following members:
5.6.1 Chair, who must be not directly involved in the management of the institutional animal care facilities, nor the clinical veterinarian for the University, and not be involved in preparing a significant number of animal use protocols.
5.6.2 A minimum of two and a maximum of four full-time continuing faculty members experienced in animal care and use in research, testing, or teaching, who may or may not be actively using animals during their term on the AREB.
5.6.3 One veterinarian licensed in Alberta, experienced in experimental animal care and use (ex-officio).
5.6.4 One current University member whose normal activities do not depend on or involve animal use for research, teaching or testing.
5.6.5 A minimum of one and a maximum of two person(s) representing community interests and concerns, who have no affiliation with the University and who are not involved in animal use for research, teaching or testing.
5.6.6 A minimum of one and a maximum of two full-time student(s) of the University.
5.6.7 One Research Ethics Coordinator who provides support to the AREB (ex-officio).
5.6.8 One University Animal Care Technician (ex-officio) responsible for management of University animal facilities.
5.6.9 Other persons may be appointed on a term-to-term basis to the AREB as the need arises for specific expertise (e.g. person(s) responsible for health and safety/biosafety, biostatisticians, ethicists, public relations liaisons).
6.1 The AREB will meet at least twice per year between September 1 and June 30, and as often as necessary to fulfill its responsibilities.
6.2 Quorum for AREB meetings shall be a majority of the members including a community representative, faculty member experienced in animal care and use in research, testing or teaching, and the university veterinarian present.
6.3 In addition to meetings, the AREB must visit the animal facilities once per year.
6.4 All meetings and animal facility visits must be documented, including any discussions, decisions and recommendations.
The AREB meets monthly to review applications for animal research, teaching and testing. Applications must be submitted to AREB@macewan.ca by the application deadline in order to be reviewed at the upcoming meeting. Please see the AREB Application Guidelines for more information.
2015-16 AREB Meeting Dates
|Meeting Date||Application Deadline|
|September||Tuesday, September 15||Tuesday, September 1|
|October||Tuesday, October 20||Tuesday, October 6|
|November||Tuesday, November 24||Tuesday, November 10|
|December||Tuesday, December 15||Tuesday, December 1|
|January||Wednesday, January 20||Wednesday, January 6|
|February||Wednesday, February 17||Wednesday, February 3|
|March||Wednesday, March 23||Wednesday, March 9|
|April||Wednesday, April 27||Wednesday, April 13|
|May||Wednesday, May 18||Wednesday, May 4|
|June||Wednesday, June 15||Wednesday, June 1|
The AREB does not meet or review applications in the months of July and August. All applications for review before September must be submitted by June 1. All applications submitted after June 1 will be reviewed at the following September meeting.
Before beginning the application process, please review:
Merit Peer Review Forms
Animal Research, Teaching and Testing Forms
Animal Procurement Reporting Form (**NEW**)
The principal investigator (PI) MUST submit this form to AREB@macewan.ca minimally ten business days before requiring animals. The Animal Care Technician is responsible for acquisition of all animals.
Supplementary Forms and Appendices
- AREB Standard Operating Procedure (SOP) Form
- Animal User Training: Part II - Evidence of Training Form
- Field Research Appendix Form
- Sample Endpoint Monitoring Checklist
Animal Renewal & Modification Forms
Post-Approval Monitoring (PAM) Forms
See academic Policy C5053 - Animal Research Ethics
AREB Operations SOPs: Project Approval and Monitoring Processes
AREB Operations SOPs: AREB Membership and Responsibilities
AREB Operations SOPs: Administrative
|300.2||AREB SOP Administration|
|301.1||AREB Member and Animal User Training|
|303.1||Incident Reporting and Resolution: Animal Welfare, Morbidity and Mortality|
For copies of any Animal Care and Use SOPs, please email AREB@macewan.ca