Biological Sciences

David McFadyen

Assistant Professor, Biological Sciences

PhD (Alberta), M.Sc.(Regina), B.Sc. (Regina)

6-118J, City Centre Campus
10700 – 104 Avenue
Edmonton, AB


Dr. McFadyen completed his PhD in the Department of Biological Sciences at the University of Alberta. His doctoral research involved the application of molecular and cytogenetic methods to probe the organization and evolution of a multigene family in rodents. He completed a Post-Doctoral Fellowship in the Department of Medical Genetics at the University of Alberta where he contributed to the physical mapping efforts of human chromosome 14.

Dr. McFadyen has been a faculty member in the Department of Biological Sciences since 1998, serving as chair from 2008 to 2015. He teaches introductory, eukaryotic and human genetics. Dr. McFadyen’s research focuses on the development and application of molecular tools for probing evolutionary relationships.

Available to supervise senior students' independent study.

Genetics, molecular biology, molecular phylogenetics, DNA barcoding, genetic diversity, population structure, orchids, freshwater fishes

Teaching and Research Interests

The ability to correctly identify species, quantify genetic diversity and understand interspecific relationships are essential components of a sustainable conservation effort. Dr. McFadyen's research focuses on the application of molecular methods to understand evolutionary relationships and population structure of species experiencing natural or anthropogenic pressures.

Currently, two projects with this thematic approach are being conducted. The first project involves the creation of a comprehensive DNA barcode library of orchids within the genra Dracula and Masdevallia, initially, to investigate their evolutionary relationships through the application of the chloroplast molecular markers. The second project sets out to examine the temporal and spatial population genetic structure, using microsatellite analysis, of various fish species in Lac La Biche.

Selected Publications / Presentations / Conference Papers

  • McFadyen DA, Locke J. 2000. High Resolution FISH Mapping of the Rat 2u-Globulin Multigene Family. Mammalian Genome 11:292-299.
  • McFadyen DA, Addison W, Locke J. 1999. Genomic Organization of the Rat 2u-Globulin Gene Cluster. Mammalian Genome 10:463-470.
  • Wang KS, McFadyen DA, Locke J, Hodgetts RB. 1997. Three Subsets of Genes Whose Tissue Specific Expression Is Sex and Age-Dependent Can Be Identified Within the Rat 2u-Globulin Family. Developmental Genetics 21:234-244.
  • Chapco W, Kelln RA, McFadyen DA. 1994. Mitochondrial DNA Variation in North American Melanopline Grasshoppers. Heredity 72:1-9.
  • Chapco W, Kelln RA, McFadyen DA. 1992. Intraspecific Mitochondrial DNA Variation in the Migratory Grasshopper, Melanoplus sanguinipes. Heredity 69:547-557.